Known to me:
1) Spells Cooldowns
Independent to Items cooldown
2) Items USE Cooldowns: [Potions, Runes, Tools, Weapons]
Runes apply also attack/healing/support spell cooldown
3) Items EQUIP Cooldowns
Looks like it is 100 ms. I can not equip 2 items pieces at the same time I need to wait approx 100 ms.
4) Loot from floor cooldown
(sometimes I have to click twice if I do it very fast, it's due to keystroke delay? I have set it to 100 ms)
5) Items OPEN Cooldowns?
Do you know more limitations and correlations and dependencies between them? Meaby do you know the exact numbers?
Generally, what do you know abut this topic?
I recognise if I use rune 100-200 ms b4 exhaust ends I will trow it immediately. I am looking for details like that.