Yes, it is!!.To do that, go to the imbuing shrine, select the weapon which you want to remove the imbuement.Then select the imbuement that you want to remove (to select the imbuement you have to click the displayed square of the imbuement) and click the big button on bottom right that says "Clear Imbuement". Removing an imbuement will cost 15,000 gold coins and it removes just the selected imbuement. If you want to remove more than 1, then you have to manually select one at a time and pay 15,000 gold for each one of them.
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