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Life drain protection is considered as most useful type of defense (along with physical). What is the highest possible rate of protection against life drain?

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Best answer

There aren't many items that give us life drain protection.

The best protection you can have is 57,75% by using:

 

ItemProtection
 Necklace of the Deep50%
 Ring of Souls10%
 Bone Fiddle5%

People tend to use Garlic Necklace (20% res) due to its price 

+2 votes
by (479 points)

Here is a list of all the items you can use to protect yourself against life drain, however, there are no armors, legs, helmets, shields or weapons protecting against life drain.

Rings
NameProtectionDurationRequired level
Ring of soulsPhysical +2%, Life drain 10%2 hours200

Amulets and necklaces
NameProtectionChargesRequired level
Garlic NecklaceLife drain +20%150
Necklace of the DeepLife drain +50%50120

Light sources (Arrow slot)
NameProtection
Bone FiddleLife drain +5%

Source: https://tibia.fandom.com/wiki/Life_Drain

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