ey, with runes like dodge you will take less damage and with attack runes you will do more damage, so the exp will go up. You have to pay attention if the monsters you hunt are weak to some element and put the charm of that element to that monsters , so it will receive even more damage. The critical rune is usually good in hunts with monsters with low health, 8k and below.
In place like rotten golems, you can put fire, death and physical charms, they receive more damage from these elements, and you will hit the 5% of the charm + the X% extra they receive from thoose elements (more than 1.5k hp)