Hello friend, you are little wrong.
The only moment its worth to unequip your weapon is when u finish your hunt and you dont want to lose imbues xDDDD
Its true that our weapons (wands and rods) have super low damage, but u have to take in consideration 3 stuff:
1 - You always can trigger your charm with your autoatack (or basic atack) - Imagine hitting for 100 hp to branchy crawler (27k hp - Curse charm).
5% of 27.000 is 1350 // Branchy Crawler takes 115% of death damage - TOTAL DAMAGE 1.552 + autoatack damage (between 80 and 120)
2 - Every single hit for your weapons will trigger your imbues, its a good way to optimice your hunts, getting some extra mana and life lich.
3 - Thats a personal tip, but after tibia added music to the game, u can use this "autoatack sounds" as a "timer". For example as druid, autoatack have 2 seconds, exactly the same than exura gran mas res, then every hit on rod, means i have to use exura gran mas res.
But this can work for all rotation, im waiting for this sounds to start - potion heal potion heal atack utility
I understand this can be little crazy but after some months of practique now i can "play without looking" cause i only have to hear this autoatack then starts with the rotation.
I hope i helped you with my answer!
Grettings Gleemody