I'm going to make some assumptions based on general information I'm aware of. We all know that every Rotten Blood hunting ground has some sort of special extra damage system that makes every location more dangerous.
Putrefactory - Can randomly spawn Root Totems from respawn that do massive death damage and can catch players off guard if they are low on health. Using a Stone Skin Amulet in this situation can be very useful.
Jaded Roots - When a creature dies, a Decaying Totem can appear in its place that unleashes great earth damage and can also catch players off guard if health is low. Climbing a Sacred Tree Amulet can reduce some of this damage.
Gloom Pillars - If the contactor on the characters side reaches 100 it will explode a very powerful chain energy damage that can reach up to 05 players can reach up to 6000 damage. If you can get away from the players, part of this running can be avoided.
Darklight Core - A darkfield can appear below players and deal a cumulative amount of Agony damage. There is no way to reduce this type of damage but these fields can be broken with a Destroy Field Rune.
So taking this information into account, I'm going to create some hypotheses.
In Putrefactory and Jaded Roots, in addition to the damage of these mechanics, if a creature dies close to it, it will cause even more damage, but both damage can be reduced with amulets and Might Ring. Even so, if the players are dealing with a lot of creatures at the moment and still negative effects of the Taint, one of these situations can be fatal.
In the case of the Gloom Pillars, the current of powerful energy can reach several players and if one of them doesn't have enough protection, it can be fatal too. Then we come to what feels like the toughest of them all: Darklight Core.
As we know there is no kind of data protection for agony but remember that these darkfield here have two advantages. One is that they can be removed from the ground using a Destroy Field Rune. The second advantage relative to the hunting team is that it won't hit nearby players all at once.
When the darkfielf appears on players they may have previously created a shortcut to the Destroy Field rune with "use it on yourself" and if they are quick enough they will only take the initial Agony damage and not the full extent of it.
So, as complex as it may seem, I believe that the Darklight Core hunt has the potential to be the best hunt in tibia right now. Obviously it must be taking into account the level of the players to face the creatures of the place and their equipment and prey system to reduce the greatest amount of damage possible.