Hello, I think best charm rune for this spawn is Freeze, as these creatures are weak to ice attacks (125%). Second rune I would recommend is Dodge - in order to make yourself more safe while hunting. You can also consider Wound, if you feel comfortable on the spawn. I would go Freeze on Werelion and Dodge/Wound on Werelioness (this one is stronger). You should also consider wearing Holy/Fire protection as they can deal some nice damage with combos.